DNA Complement

Convert DNA sequences to their complementary strand using Watson-Crick base pairing rules.

DNA Strand Pairing

5' → 3':
3' ← 5':

What is DNA Complement?

DNA Complement generates the complementary strand of a DNA sequence using Watson-Crick base pairing rules: A pairs with T, and C pairs with G. Unlike reverse complement, this tool only performs complementation without reversing the sequence direction.

How to Use This DNA Complement Tool

Get complementary DNA sequences instantly:

  1. Paste or upload your DNA sequence
  2. Complement appears automatically
  3. View visual strand pairing
  4. Copy or download results

When to Use

This tool is useful when you need to:

  • Find the complementary DNA strand
  • Design primers and probes
  • Understand base pairing in double-stranded DNA
  • Convert between sense and antisense strands

Example Input

Original DNA sequence:

5' ATCGATCGATCG 3'

The tool will generate its complement.

Example Output

Complement sequence:

3' TAGCTAGCTAGC 5'

Note: A→T, T→A, C→G, G→C

FAQ

Q: What's the difference from reverse complement?
A: Complement only changes bases, reverse complement also reverses the sequence.

Q: Does it handle IUPAC ambiguous codes?
A: Yes, supports all IUPAC nucleotide codes (R, Y, N, etc.)

Q: Does it preserve sequence case?
A: Yes, maintains uppercase/lowercase from input.