Generate DNA sequences with defined regions of different compositions for modeling complex genomic structures
DNA regions are sections of a sequence with distinct compositional properties. Real genomes have regions with varying GC content, CpG islands, AT-rich introns, and GC-rich exons. This tool lets you create sequences mimicking these structures.
Create multi-region sequences in three steps:
This tool is useful when you need to:
Typical gene structure:
Region 1: 200bp, 70% GC (promoter) Region 2: 500bp, 45% GC (exon) Region 3: 300bp, 35% GC (intron)Generated sequence structure:
GCGCCGCGATCG...ATGCTGACC...ATTATATAAA...Total length: 1000bp with distinct regional composition.
Q: What does GC content control?
A: The percentage of G and C nucleotides vs A and T in each region.
Q: Can regions overlap?
A: No, regions are concatenated sequentially in the order added.