Shuffle Protein

Randomly shuffle protein sequences while preserving amino acid composition. Perfect for generating control sequences for statistical analysis.

What is Shuffle Protein?

Shuffle Protein randomly rearranges amino acids in a protein sequence while maintaining the exact same composition. This creates randomized control sequences for statistical significance testing in protein analysis.

How to Use This Shuffle Protein Tool

Generate shuffled sequences instantly:

  1. Paste or upload your protein sequence
  2. Sequence is automatically shuffled
  3. Click "Shuffle Again" for new randomization
  4. Copy or download shuffled result

When to Use

This tool is useful when you need to:

  • Create null hypothesis controls for protein analysis
  • Test significance of sequence motifs
  • Generate random sequences with specific composition
  • Validate protein pattern finding algorithms

Example Input

Original protein sequence:

MKWVTFISLLLLFSSAYSRGVFRR

Try with the Example button.

Example Output

Shuffled (same composition):

LVFSSIRGLWFKYLLMTRVRSAFS

Same amino acid counts, different order.

FAQ

Q: Are amino acid properties preserved?
A: Only composition is preserved, not structure or properties.

Q: Can I shuffle multiple proteins?
A: Yes, FASTA format with multiple sequences is supported.